Vascular calcifications are the consequence of several pathological conditions such as atherosclerosis, diabetes, hypercholesterolemia and chronic renal insufficiency. They are associated with risks of amputation, ischemic heart disease, stroke and increased mortality. A growing body of evidence indicates that vascular smooth muscle cells (VSMCs) undergo chondrogenic commitment eventually leading to vascular calcification, by mechanisms similar to those governing ossification in the cartilage growth plate. Our knowledge of the formation of cartilage growth plate can therefore help us to understand why and (...) how arteries calcify and, consequently, develop new therapeutic strategies. Reciprocally, thorough consideration of the events leading to ectopic chondrocyte differentiation appears crucial to further increase our understanding of growth plate formation. In this context, we will review the effects of known or suspected factors that promote chondrogenic differentiation in growth plate and arteries. BioEssays 27:708–716, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

The development and use of nanotechnology in the food industry have grown steadily. While visions for nanofood suggest that the applications will improve quality and safety, they are also controversial for several reasons including potential health risks coupled with difficulty in assessing low-dosage nanoparticle risks as well as values-based objections. In recent years, debate over nanofoods has sparked inquiry into factors that predict public attitudes and purchase intentions. Such studies have investigated the roles of demographics and sociographics, value predispositions toward (...) science and technology, preferences for natural products, trust in regulatory agencies, scientific knowledge, and media attention. This study assesses the role of each of these factors in shaping public attitudes toward nanofood and improves the predictive models by evaluating concepts from protection motivation theory. We find that incorporating threat and coping appraisals provides the best predictive models of public attitudes and intention to purchase nanofood products. (shrink)

We applaud Ray and Cooper (2024) for emphasizing environmental health as a bioethics issue. As a team of interdisciplinary pediatric researchers and providers who are part of an institutional clima...

Several target articles in this BBS special issue address the topic of cerebellar and olivary functions, especially as they pertain to motor earning. Another important topic is the neural interaction between the limbic system and the cerebellum during associative learning. In this commentary we present some of our data on olivo-cerebellar and limbic-cerebellar interactions during eyeblink conditioning. [HOUK et al.; SIMPSON et al.; THACH].

Volume 20, Issue 5, June 2020, Page 38-40.

Under the balmy Mediterranean skies of Santa Margherita Ligure on the beautiful Italian Riviera, forty Hegelian scholars from nine countries put their heads together on the theme “Hegel’s Philosophie des subjectiven Geistes” at the Conference of the Internationale Hegel-Vereinigung, May 24–27, 1973. Enjoying the generosity of the Italian Government and the official hospitality of the Municipality of Santa Margherita, the participants heard and discussed four papers by German scholars, two each by Italians and Americans, and one each by a Dutch (...) and a French scholar. Professor Valerio Verra of the University of Rome served as host, and Professor Dieter Henrich, President of the Internationale Hegel-Vereinigung, introduced the theme of the Conference and officiated the proceedings. Chairing individual sessions and participating in the discussions were such internationally known figures as Hans-Georg Gadamer of Germany, Eric Weil and Marcel Régnier of France, W. H. Walsh and Anthony Kenny of Great Britain, and Enrico de Negri of Italy. (shrink)

It may be that Kant manifested a profound understanding of modern empirical science in his observation that we have now placed nature on the witness stand and are compelling her to answer the questions we think fit to propose. This, I am convinced, is not the approach best suited to bring out the deepest insights and systematic teachings of another philosopher. On the contrary, it would seem that one can make sense out of another man's thought only by coming to (...) know how that person sees the problem, and what he regards as an adequate solution to it. If this is correct, one of our first objectives should be to see how Weiss sees the problem of knowledge and what he regards as the requirements for an adequate account of human knowledge. (shrink)

The 14th International Congress of Philosophy, held late last summer in Vienna, had an entire subsection devoted to Hegel. Several papers were presented by philosophers from America, including: "Hegel In Light of His First American Followers", by Professor Loyd D. Easton of Ohio Wesleyan University; "Hegel and Husserl", by Professor W.H. Werkmeister of The Florida State University; "Hegel's Theory of Signification & The Origin of Dialectic", by Professor Daniel Cook of Herbert H. Lehman College ; "Beginning the System: Kierkegaard and (...) Hegel", by Professor Robert Perkins, University of South Alabama. These papers and others will be published in the Congress Proceedings. Inquiries should be directed to the University of Vienna Department of Philosophy. * * * Professor H.S. Harris of Glendon College, York University, Toronto, will shortly have published in a volume titled Essays in Honour of Max Fisch "The Fragment on Faith and Being in Hegel's Early Theological Writings". The essay contains the text translation and a full commentary on the fragment Glauben und Sein in Nohl. * * * The Fall issue of Philosophy Today contain an article by Professor Howard P. Kainz of Marquette University titled "Hegel's Characterization of Truth in the Phenomenology". * * * James F. Donaldson of Texas Technological College has an article titled "The Origin of Hegel's Dialectic" in the current issue of Lavel Theologique et Philosophique. A brief abstract of the paper may be found in the Fall, 1969 Philosopher's Index. (shrink)

(1979). THE SCIENCE OF LITERATURE METHOD OF PROF. M. WEISS IN CONFRONTATION WITH FORM CRITICISM, EXAMPLIFIED ON THE BASIS OF Ps. 49. Bijdragen: Vol. 40, No. 2, pp. 152-167.

Contains three lectures on vaguely related topics. John Cogley outlines the sources of religious conflict in the United States. Holding that the First Amendment was intended not to discourage religion but to promote religious liberty, he develops principles for the solution of problems of Church-State relations. Paul Weiss discusses the more theoretical problem of the relationship of natural and supernatural law. Natural law derives from a common good relative to a particular group, and is strictly utilitarian. Reference to a (...) supernatural or divinely given good is necessary to adjudicate between and order the differing and possibly conflicting common goods of different groups, and to provide for ethical laws that transcend utilitarian considerations. John Wu sees the main prerequisite of a future world democracy as a meeting of the insights and cultures of the East and West.--A. F. G. (shrink)

Despite the skepticism of many mathematicians and logicians as to the possibility of any test which will show conclusively the consistency or independence of the members of a postulate set, several methods have nevertheless been devised and employed, e.g., the empirical methods of Russell and Huntington, the internal method of Hilbert, and the reflective method of Royce. However, with the possible exception of Hilbert's method, these techniques require us to forsake the purely formal or abstract mode of analysis, and instead (...) to rely in some sense on “concrete representations” or “interpretations” or “modes of action” which are said to “satisfy” the postulates in question. In short, they are all interpretational methods—and here is the crux of the problem. “Is it possible,” queries Weiss, “that the only way we can determine whether a set is consistent is by seeing all the postulates actually exemplified in some object? If so, we must arbitrarily assume that the object is self-consistent, so that the proof of consistency must ultimately rest on a dogma. As independence rests on consistency there are therefore no satisfactory proofs as yet of either independence or consistency.” The question “is thus answered,” according to Young, “only by reference to a concrete representation of the abstract ideas involved, and it is such concrete representations that we wished especially to avoid. At the present time, however, no absolute test for consistency is known.” Moreover, “suppose,” says the late Dr. Eaton, “that the system has no interpretation: how can the consistency independence … of the postulates be shown? There should be some analytic way—purely in the realm of the abstract, without interpretation—of establishing these properties of a set of postulates. This is an important problem that awaits solution.”. (shrink)

Five essays on various aspects of Peirce's philosophy, first delivered as a series of lectures at Yale University, plus a brief biography of Peirce by Paul Weiss. The essays are: "Charles S. Peirce as an American," by Rulon Wells, "Notes Toward a Logic of Discovery," by N. R. Hanson, "Action, Conduct, and Self-Control," by R. J. Bernstein, "Community and Reality," by J. E. Smith, and "Charles S. Peirce, Philosopher," by Paul Weiss. Several of these essays contain concise, perceptive (...) summaries and evaluations of Peirce's thought in various areas; the book is an excellent introduction to Peirce's philosophy.—P. F. L. (shrink)

In this work, Weiss presents his latest views on the fundamental questions of being and knowing which have concerned him throughout his career. He seems to have accepted his own challenge "... that were I to take advantage of what is said in Philosophy In Process and revise the Modes of Being, the result, in effect, would be a new philosophic ‘Aristotelianized’ account." Here, "Aristotelian" refers to any systematic attempt to give categories to "map the universe." This is, in (...) part, the thrust of Beyond All Appearances. This work, like Weiss’ others, bristles with his idiosyncratic technical vocabulary ; but that vocabulary is well controlled here. Unstintingly an effort in speculative metaphysics, this is also a highly readable book. (shrink)

Ob was Mythos im ursprünglichen oder anfänglichen Sinn heissen soll aus den zahlreichen späteren und sich oft widersprechenden Deutungen überhaupt noch ans Licht zu ziehen ist lässt sich fragen. Desgleichen, ob es das Sein selbst ist, das sich im Mythos (als auslegende Seinserzählung) dem archaischen Menschen kund tut oder ob es vom Menschen als dem „interpretations- und orientierungsbedürftigen Wesen” angesprochen wird. Im ersten Falle lässt Mythos sich am besten als Manifestation, im zweiten als Interpretation auffassen. Aber auch wenn es das (...) Sein selbst sein sollte, das den Menschen im Mythos anspricht so ist es auf ihn als das Wesen, das ausspricht dass es angesprochen wird oder sich angesprochen weiss immer noch angewiesen. Die immer von aktuellen Fragen inspirierte wissenschaftliche und philosophische Forschung wird mit der Schwierigkeit konfrontiert, dass die Suche des Mythos „an sich” immer davon auszugehen hat was der Mythos „für uns” bedeutet und dem unmöglich los wird. Wenn Myhos mit einem gewissen Recht als „vorgängiges Seinsverständnis” qualifiziert wird kann mit gleichem Recht gelten, dass jede theoretische Interpretation des Mythos als Artikulierung von etwas das „vorgängiges Mythosverständnis” genannt werden kann aufzufassen ist. Der Grund, der im Mythos gelegt wird, lässt sich nicht mehr „interpretationsfrei” zurückholen. Zugleich zieht er uns immer wieder zu sich zurück. Auch das ist ein Grund – der Grund, der uns zwingt immer wieder vom Mythos zu reden und über ihn nachzudenken, sei es im Modus des Verfalls. (shrink)

This brief, well-written book expands Weiss’ philosophy of art to include the making of films, and in doing so helps one to better understand much of his philosophy as a whole. For example, the shift from Modes of Being to Beyond All Appearances can partly be understood as the fuller appreciation of what actualities are that has followed from Weiss’ further reflections on the status of art objects. The book presents an argument which is shaped by an exemplary (...) structure, divided into three parts. Part I begins with a definition of film as "... a created visual ordered whole of recorded incidents, providing one with a controlled emotional introduction, primarily to Existence...". The first half of this definition is developed by isolating five essential parts appropriate to any art film: 1) the script, 2) performers, 3) "cinemakers," 4) montagists, and 5) the director. This analysis of part and whole is bolstered by showing how each part can obscure all the others, thus leading to five varieties of art film. None of these, however, is as likely to be great art as is a sixth, in which "... a scriptist makes a film intelligible, a performer gives it focus, a cinemaker enables it to be seen and heard, a montagist distinguishes it from the outcomes of all other efforts, and a director unifies it.". (shrink)